Botox vs. Xeomin -by Dr. TomaselloXeomin (Zee-Oh-Min) from Merz Aesthetics has been used in Europe since 2008. It received FDA approval in November of 2011 and is the newest Neurotoxin on the US market. However, Xeomin (inco-botulinumtoxinA) did not come out of the gate smoothly. It was pulled in March of 2012 following a federal court ruling that Merz collected consumer lists and sales figures from Allergan (the maker of Botox). The confidential information was obtainedthrough Allergan sales representatives. So after a rocky start, it was re-launchedin early 2013. Botox and Xeomin are very similar. Xeomin is sometimes described as The Naked Botox due to its absence of the carrier proteinspresent withBotox. In theory this absence of protein carriersresults in fewer allergic reactions or resistance to the neurotoxin. Xeomin, due to its lack of these additives, does not need to be refrigerated. It is the only one of the three neurotoxins that has this feature.
Lets discuss these advantages
- In theory, less people will develop resistance via antibody formation. If you have a cold, the body makes antibodies to fight off that virus. When that virus comes around again, the antibodies quickly neutralize it. Hence, the body is resistant.The human body doesnt commonly make antibodies to Botox In the small percentage that do, the effect and duration of action of Botox are markedly reduced. In the very few patients I have seen with this resistance, I switch to Dysport.
- In theory, fewer allergic reactions. Merz aesthetics attributes this to the absence of carrier proteins as well. After injecting Botox for over 10 years I can honestly say I have neverexperienced a patientallergy to Botox.James Bonaparte, MD, Cosmetic Surgeon and researcher would seem to agree as he notes, After reviewing 20,000 patients and a number of randomized studies, there are no reports of allergies with Botox.
- No refrigeration needed. Botox and Dysport are shipped in dry ice. Hence, Xeomin is cheaper to ship and adds a measure of convenience here.